This chapter provides a roadmap for any who are inspired to start a teen science café program as a member of the teen science café network. These out-of-school programs are a free, fun way for teens to explore the advances in science and technology affecting their lives. Teens and scientists engage in lively conversations and activities to explore a topic deeply. Teens get increased understanding of the nature of science and develop a realistic perception of scientists, science careers, and the lives they lead. Scientists gain skills in communicating science to the public and inspire youth to STEM careers. Adult leaders serve as guides for the teen leaders and are the linchpin of the program. Evaluation shows programs positively influenced teens understanding of science issues in the news, the ability to use facts to support scientific points of view and considering multiple sides of an issue before making a decision.